Learn about fertility tests and investigations

In this guide

If you’re been struggling to conceive for several months or know you’ll need treatment to be able to conceive, it’s time to get help from professionals. These doctors and specialists will be your go-to team to help you figure out what’s going on and your next steps. 

Who are the medical professionals I can reach out to?

Depending on your situation and stage of the journey, here are key team members to know, and what their specialties are:

  • Andrologists: Physicians who specialize in male reproductive health. These doctors typically work in andrology labs, which offer diagnostic tests to help doctors determine causes of male factor infertility. Because they work in labs, you likely won’t deal with an andrologist directly.
     
  • Obstetrician/gynecologists (OB/GYNs): The go-to doctors for women’s reproductive health, from yearly check-ups all the way through labor and delivery. They’re a good place to start your fertility journey, and if you need care that extends beyond what their practice covers, they’ll refer you to a fertility clinic.
  • Reproductive endocrinology and infertility (REI) doctors: Board-certified doctors who specialize in infertility. They often work in fertility clinics and treat patients directly. 
  • Reproductive urologists: Board-certified doctors who train in infertility and specialize in male factor infertility diagnoses.
  • Fertility specialists: This is a catchall term that can include reproductive endocrinologists, andrologists, and advanced staff at a fertility clinic.

What’s the difference between an OB/GYN and an REI? 

REIs can run a lot more diagnostic tests from their office, like a semen analysis, HSG, hysteroscopy & more. They have more experience interpreting the results, and overall, it's just more likely that they've seen patients like you. REIs can also treat men and women, whereas OB/GYNs treat women exclusively.

REIs can also offer a full range of fertility treatments, which won't be available to you at your OB/GYN, like IVF treatment. Our take: If you know you’ll need treatment, it's better to see an RE that you like sooner rather than later.

And for those with male factor infertility, it actually may be better to consult a reproductive urologist over an REI. Urologists work directly with men and are experts in diagnosing and addressing male factor fertility concerns. They can work collaboratively with REIs to help come up with a plan for both partners. 

When should I see a doctor?

According to the American Society of Reproductive Medicine’s official guidelines, women under 35 should see a doctor after 12 months of well-timed intercourse without conceiving a child, and women over 35 should see a doctor after 6 months of trying without conceiving.

There are situations when it’s best to see a doctor earlier, including if any of the following apply to you: 

  • Family history of infertility or early menopause
  • 3 months of irregular periods, or no period at all 
  • Past chemotherapy, which can impact the reproductive organs
  • More than one miscarriage that you’re aware of (Note: Many people miscarry without even knowing they’re pregnant.)
  • Suspected, or diagnosed, endometriosis
  • Prior surgery on the uterus or ovaries
  • Female history of appendicitis
  • For men only: Medical history that includes a groin injury, surgery for a hernia, or exposure to substances like asbestos, pesticide, or formaldehyde

Suggestion: Get an appointment on the books a little early. You can always cancel if you don’t need it.

If you’re flexible about the doctor you see for treatment, you’ll have more options and may be able to be seen quickly, but if you need to see a specific provider for your particular case, you might have to wait — in fact, some doctors don’t have appointments available for new patients for several months. 

If you’re considering treatment, it’s worth making an appointment for several months out if you need to see a specialist with a long waiting list. You can always cancel your appointment if you don’t end up needing it or decide it’s not the right time to go through treatment.

Do I need a referral to work with any of these doctors, or can I just make an appointment directly?

It depends on the doctor and the specialty! You can call and schedule appointments with REIs and OB/GYNs anytime.

You’ll need a referral to see some specialists, like a urologist, because you’ll usually do tests first and be referred to a specialist if your test results come back abnormal.

That said, sometimes a referral can help you get an appointment on the books sooner, even for an REI. It’s always worth asking your primary care doctor or OB/GYN for a referral if you’d like to be seen sooner rather than later. 

What does insurance generally cover?

Irritating answer: It depends. Some plans will cover a surprising amount of diagnostic testing, so it’s worth checking with your insurance about coverage before starting the process or asking your clinic’s finance department.

But there is a plus: You don’t have to figure out your insurance coverage by yourself. Fertility clinics have a dedicated billing department with insurance specialists, and they’re there to help make the most out of your coverage. They’re experts in understanding and navigating the healthcare system, and they’ll be able to tell you what is and isn’t covered in your specific health care plan.

What kinds of tests happen at a consultation? 

A first appointment generally starts with a one-on-one conversation with your doctor about your medical history, goals, and timeline. After you talk, you’ll go back to an exam room for a series of tests and scans.

Your test results help you and your doctor a) understand your fertility; b) assign a diagnosis, if needed; and c) create an action plan. 

“I wish someone had told me that…”

There’s no need to dress up for your consultation and every clinic visit — we recommend wearing a short sleeved top and bottoms that are easy to put on and take off. Here’s why: You can expect to have a transvaginal ultrasound and to have at least one vial of blood taken at every visit. 

There’s usually no need to fast before your appointment, but you can always ask your nurse beforehand to be sure. 

Blood tests 

At your first visit, a nurse will take several vials of blood and run lots of tests. Here’s an overview of the tests that might apply:

AMH (anti-Müllerian hormone)

What it does: Estimates egg quantity

What it tests: Hormone levels of dormant follicles in the ovaries that house eggs

What the results tell your doctor: A high AMH means there are many follicles left on the ovaries, and a low AMH means there are fewer.

FYI: AMH levels typically don’t change a lot during the menstrual cycle, so it can be tested anytime without shifting substantially. That said, if you’re taking hormonal birth control, your AMH level may show up as lower than it actually is. Tell your doctor if you’re on birth control. 

FSH (follicle stimulating hormone)

What it does: Estimates egg quantity

What it tests: A hormone released by the brain that signals ovarian follicles to grow and develop. If an ovary is working properly, it only needs a small amount of FSH to signal a dominant follicle to grow. If that ovary isn’t working properly, it will take more FSH to kickstart a dominant follicle to begin maturing an egg — that means a higher level of FSH is needed (and found) in the bloodstream.

What the results tell your doctor: A high FSH (more than 10) is associated with a lower number of eggs retrieved in an IVF cycle.

Ultrasound tests

Your doctor will perform a transvaginal ultrasound to check the structure of your reproductive system and to see the number of visible egg follicles. They’ll be able to tell when you’ll ovulate next based on this visual, which is kind of a trip. 

AFC (antral follicle count)

What it does: Counts the number of follicles in your ovaries, which can indicate how many eggs might be released for egg collection.

What it tests: How many follicles are mature, which can indicate how many you’ll be able to stimulate with hormonal medication.

What the results tell your doctor: If you decide to move forward with treatment, you’ll have your AFC checked regularly to see how your body is responding to medication. Low AFC can indicate a poor response to fertility medications

Additional tests

Depending on the outcomes of those tests, your doctor might recommend a few other tests: 

HSG (hysterosalpingography): Checks the fallopian tubes’ health and structure, including finding any blockages

Hysteroscopy: Checks the cervix and uterus’ structure, including looking for polyps or fibroids that could impact your ability to conceive

Genetic carrier screening: Checks blood samples from both partners for inheritable genetic conditions that could be passed down to your children

Tests specifically for men

Semen analysis

What it does: Gives a doctor an understanding of a man’s sperm health and can highlight any concerns about sperm’s quality or quantity

What it tests: pH, volume, density, morphology (shape), motility (speed), liquefaction (time it takes to go from sticky to fluid), vitality (percent of live sperm) and white blood cells (to test for any infections or inflammation) 

The process: Masturbate (either at home or at a fertility clinic) to provide a semen sample for a doctor to test

What the results tell your doctor: Whether a male partner’s sperm has any problems that could keep it from fertilizing an egg

Wrapping up

This sounds like a lot, but many people won’t need all of the tests. Most people will start with egg quantity tests, and your doctor will order more tests as needed. 

As you go through your initial testing, reach out to your care team (or if you’re a Gaia Member, your Gaia Advocate!) any time you have a question. We’re all here to help. 

Written by
So far I am very happy with Gaia
So far I am very happy with Gaia, I am about to have my first try of IVF with them, I have found them extremely helpful and all the staff I have delt with have been so kind and friendly. I would recommend using Gaia.

Laura

Published 2 Oct 2023
Gaia makes the world a happier place
Gaia are so friendly, welcoming and kind! We were so so excited to hear about Gaia when we attended a open evening at Bourn Hall Wickford. It is the most amazing gift that Gaia can give to a person/persons, they put fertility treatment...

Mrs Sarah Prince

Published 17 sep 2023
Gaia is my family too!!!
I haven't started my treatment yet but till this point I'm very happy with Gaia family. I don't have words to express my gratitude and I'm sure with their help I will have my baby soon. The communication have been excell...

Gabriella

Published 8 jul 2023
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Arizona

New Jersey
RMA New Jersey - Princeton
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
New Jersey
RMA New Jersey - Somerset
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
New Jersey
RMA New Jersey - Springfield
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
New Jersey
RMA New Jersey - West Orange
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
California
RMA Northern California - East Bay Danville
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
California
RMA Northern California - Palo Alto
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
California
RMA Northern California - San Francisco
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
Pennsylvania
RMA Philadelphia
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
Pennsylvania
RMA Philadelphia - Abington
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
Pennsylvania
RMA Philadelphia - Langhorne
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
Pennsylvania
RMA Philadelphia - Lehigh Valley
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
Pennsylvania
RMA Philadelphia - Wayne
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
California
RMA San Diego - Pearl Mini IVF
Pearl Mini-IVF offers a different approach to IVF, using less stimulation medication than other clinics' protocols. For patients concerned with egg quality, the targeted approach can result in better chances of a healthy pregnancy without using as many hormonal medications.
Washington
RMA Seattle (FKA Sound Fertility) - Bellevue
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
Washington
RMA Seattle (FKA Sound Fertility) - Seattle
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
California
RMA Southern California - Burbank
RMA Southern California – Burbank offers comprehensive fertility care, including testing, IVF, IUI, egg freezing, and genetic screening. With advanced treatment options and personalized support, the clinic helps individuals and couples move confidently through their family-building journey, including third-party reproduction, ovulation induction, and LGBTQ+ family-building services.
California
RMA Southern California - Laguna Hills
RMA Southern California offers advanced IVF and personalized fertility care, combining expertise with compassion to support patients on their journey.
California
RMA Southern California - Los Angeles
Reproductive Medicine Associates (RMA for short) is a global network of clinics specializing in reproductive medicine, assisted reproduction, research, and exceptional patient care.
California
RMA Southern California - Mission Viejo
RMA Southern California offers advanced IVF and personalized fertility care, combining expertise with compassion to support patients on their journey.
California
RMA Southern California - Newport Beach
RMA Southern California offers advanced IVF and personalized fertility care, combining expertise with compassion to support patients on their journey.
Utah
Reproductive Care Center - Clearfield
With over 25 years of experience, RCC’s Clearfield clinic offers expert fertility care close to home — serving Northern Utah and beyond with advanced treatments and personalized support, now strengthened through its partnership with Boston IVF.
Utah
Reproductive Care Center - Sandy
RCC’s Sandy clinic is home to a state-of-the-art IVF lab and full-spectrum fertility services — offering expert diagnosis and advanced treatments like IUI, IVF, and embryo transfers. With over 25 years of experience and a partnership with Boston IVF, RCC delivers trusted, compassionate care across the Intermountain West.
Ohio
Reproductive Gynecology & Infertility (RGI) - Akron
For more than 30 years, RGI Akron has helped patients in Northeast Ohio grow their families with expert fertility care. Located in Akron, OH, the clinic provides comprehensive services such as IVF, IUI, egg freezing, genetic testing, and inclusive LGBTQ+ family-building options — delivered with compassionate, personalized support at every step.
Ohio
Reproductive Gynecology & Infertility (RGI) - Canton
RGI Canton has been serving the community since 1992, offering advanced fertility care to help individuals and families achieve parenthood. Located in Canton, OH, the clinic provides a wide range of services — including IVF, IUI, egg freezing, genetic testing, and dedicated LGBTQ+ family-building programs — delivered with compassionate, individualized support.
Ohio
Reproductive Gynecology & Infertility (RGI) - Cleveland/Independence
Since 1992, RGI Independence has provided expert fertility care to individuals and families throughout Northeast Ohio. Conveniently located in Independence, the clinic offers comprehensive services—including IVF, IUI, egg freezing, genetic testing, and LGBTQ+ family-building programs — supported by a compassionate team dedicated to personalized care and successful outcomes.
Ohio
Reproductive Gynecology & Infertility (RGI) - Westerville
RGI Columbus has been helping patients grow their families since 1992, offering advanced fertility treatments with personalized, compassionate care. Located in Columbus, OH, the clinic provides services such as IVF, IUI, egg freezing, genetic testing, and inclusive LGBTQ+ family-building programs, supporting every path to parenthood.
Ohio
Reproductive Gynecology & Infertility (RGI) - Youngstown
Since 1992, RGI Youngstown has supported individuals and families in their journey to parenthood. Located in Youngstown, OH, the clinic offers a full range of fertility services, including IVF, IUI, egg freezing, genetic testing, and LGBTQ+ family-building programs — all with personalized, compassionate care.
California
Reproductive Sciences Medical Center
Reproductive Sciences Medical Center (RSMC) is a trusted fertility clinic offering advanced, patient-centered care through its unique all-in-one treatment model. As a pioneer in fertility services, RSMC combines medical expertise, on-site laboratory facilities, and personalized support under one roof—making fertility treatment more efficient, affordable, and accessible. This integrated approach is designed to streamline the IVF journey, reduce wait times, and improve outcomes. Whether you're exploring IVF, egg freezing, or other fertility options, RSMC is committed to helping you build your family with compassion, innovation, and care.
Washington
SRM (Seattle Reproductive Medicine) - Bellevue
Seattle Reproductive Medicine has served the Bellevue community since 2004, offering IVF, egg freezing, genetic testing, IUI, and LGBTQ+ family-building programs to help patients achieve their dreams of parenthood.
Washington
SRM (Seattle Reproductive Medicine) - Everett
Seattle Reproductive Medicine in Everett has been helping patients achieve parenthood since 2004, offering IVF, egg freezing, genetic testing, IUI, and inclusive LGBTQ+ family-building services.
Washington
SRM (Seattle Reproductive Medicine) - Kirkland
Seattle Reproductive Medicine in Kirkland has supported patients since 2004, providing IVF, egg freezing, genetic testing, IUI, and comprehensive LGBTQ+ family-building services.
Washington
SRM (Seattle Reproductive Medicine) - Seattle
Seattle Reproductive Medicine in Seattle has been serving patients since 2004, offering IVF, egg freezing, genetic testing, IUI, and inclusive LGBTQ+ family-building services.
Washington
SRM (Seattle Reproductive Medicine) - Spokane Valley
Washington
SRM (Seattle Reproductive Medicine) - Tacoma
Seattle Reproductive Medicine in Tacoma has supported patients since 2004, providing IVF, egg freezing, genetic testing, IUI, and inclusive LGBTQ+ family-building services.
California
Sama LAX
Sama offers personalized fertility care from anywhere. By working with clinics and labs near you, Sama gives you the option to conduct your imaging appointments in the comfort of your own home or local clinic and attend their Los Angeles clinic for egg retrievals and embryo transfers only.
New York
Sama NYC
Sama offers personalized fertility care from anywhere. By working with clinics and labs near you, Sama gives you the option to conduct your imaging appointments in the comfort of your own home or local clinic and attend their New York clinic for egg retrievals and embryo transfers only.
California
South Coast Fertility Center
With consistently high success rates, the South Coast team is dedicated to guiding you through every stage of your family-building journey — from your very first consultation to post-treatment follow-up. Every step of the way, you’ll feel supported, informed, and empowered with the confidence to move forward.
New York
The Albany, NY Fertility Center
Boston IVF’s Albany clinic offers convenient, local access to advanced fertility care — part of one of the most experienced networks in the U.S., serving individuals and couples across New York with innovative treatments and compassionate support.
Maine
The Bangor, ME Fertility Center
As Maine’s only IVF provider for over 15 years, Boston IVF offers trusted, local fertility care in Bangor — with access to advanced treatment through their IVF lab in South Portland, supporting patients across the state on their path to parenthood.
New Hampshire
The Bedford, NH Fertility Center
Boston IVF’s Bedford clinic is New Hampshire’s only full-service fertility center — offering in-state access to advanced reproductive care, led by award-winning specialists and a dedicated team committed to every family-building journey.
Massachusetts
The Brookline, MA Fertility Center
Boston IVF is one of the most experienced fertility networks in the U.S. Their Brookline clinic brings leading reproductive care and advanced treatments to the heart of Greater Boston, serving patients across Massachusetts and beyond.
Massachusetts
The Concord, MA Fertility Center
Boston IVF is one of the most experienced fertility networks in the U.S. The Concord clinic offers local access to advanced fertility treatments and expert care — part of a trusted network serving patients across Massachusetts and beyond.
Massachusetts
The Downtown Boston, MA Fertility Center
Boston IVF is one of the most experienced fertility networks in the U.S. Their Downtown Boston clinic offers convenient, local access to advanced fertility treatments and expert reproductive care.
Maine
The Portland, ME Fertility Center
Boston IVF’s South Portland clinic and IVF lab have been Maine’s only IVF provider for over 15 years — offering advanced fertility treatments and local, compassionate care to individuals and families across the state.
New Hampshire
The Portsmouth, NH Fertility Center
Boston IVF’s Seacoast clinic in Portsmouth is one of two New Hampshire locations dedicated to expanding local access to advanced fertility care — supported by Boston IVF’s trusted network, cutting-edge treatments, and decades of expertise in family-building.
Rhode Island
The Providence, RI Fertility Center
Boston IVF’s Providence clinic and IVF lab offer advanced fertility care in a convenient Rhode Island location — supporting individuals and couples on every path to parenthood with expert treatment and personalized care.
Massachusetts
The Quincy, MA Fertility Center
Boston IVF is one of the most experienced fertility networks in the U.S. Their Quincy clinic brings advanced reproductive care and fertility treatments closer to home for patients in the Greater Boston area.
New York
The Rochester, NY Fertility Center
Boston IVF’s Rochester clinic brings expert fertility care closer to home — offering advanced treatments and personalized support as part of a leading national network serving patients across New York and beyond.
Massachusetts
The Springfield, MA Fertility Center
Boston IVF is one of the most experienced fertility networks in the U.S. Their Springfield clinic brings state-of-the-art fertility care and advanced treatments to patients across Western Massachusetts.
Massachusetts
The Stoneham, MA Fertility Center
Boston IVF is one of the most experienced fertility networks in the U.S. Their Stoneham clinic offers convenient, local access to advanced fertility treatments and expert reproductive care.
New York
The Syracuse, NY Fertility Center
Boston IVF’s Syracuse clinic offers convenient, local access to advanced fertility care — delivering expert treatment and compassionate support as part of a nationally recognized network serving patients across New York.
Massachusetts
The Waltham, MA Fertility Center
Boston IVF’s flagship Waltham clinic is home to its largest IVF and embryology lab, award-winning fertility specialists, and comprehensive care — including wellness support and in-house gynecologic surgery — all under one roof.
Massachusetts
The Wellness Center at Boston IVF
Boston IVF’s Wellness Center, based in Waltham, MA, offers science-backed programs designed to support the emotional and physical side of fertility treatment. Opened in 2006, it provides patients across Massachusetts — and beyond — with complementary care to ease the stress of family-building.
Massachusetts
The Westborough, MA Fertility Center
Boston IVF is one of the most experienced fertility networks in the U.S. Their Westborough clinic expands access to advanced fertility care, offering personalized treatment and expert support to patients in Central Massachusetts.
Massachusetts
The Worcester, MA Fertility Center
Boston IVF is one of the most experienced fertility networks in the U.S. Their Worcester clinic offers convenient, local access to advanced fertility care — combining innovative treatments with personalized support for patients across Central Massachusetts.
Idaho
Utah Fertility Center - Idaho Falls
Utah Fertility Center delivers innovative, compassionate fertility care tailored to each patient, with a dedicated team focused on success.
Utah
Utah Fertility Center - Midvale
Utah Fertility Center delivers innovative, compassionate fertility care tailored to each patient, with a dedicated team focused on success.
Utah
Utah Fertility Center - Odgen
Utah Fertility Center delivers innovative, compassionate fertility care tailored to each patient, with a dedicated team focused on success.
Utah
Utah Fertility Center - Pleasant Grove
Utah Fertility Center delivers innovative, compassionate fertility care tailored to each patient, with a dedicated team focused on success.
Utah
Utah Fertility Center - St. George
Utah Fertility Center delivers innovative, compassionate fertility care tailored to each patient, with a dedicated team focused on success.
North Carolina
Wilmington Fertility Center
Wilmington Fertility Center understands that the journey to parenthood can be complex and emotionally challenging. From the first call to every stage of care, their team is dedicated to making patients feel respected, supported, and confident, offering expert, compassionate care tailored to each individual’s path to parenthood.
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